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human CFHR1 Over-expression AAV

Name 
AAV-h-CFHR1
Cat No 
AAV-205045
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CFHR1.

AAV-205045
AAV-h-CFHR1

Ready-to-use AAV expressing Human CFHR1 (complement factor H related 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; H36-1; H36-2; HFL1; HFL2
Description (Vector)
CFHR1 encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
Gene ID
3078
Gene Name (Vector)
complement factor H related 1
Gene Symbol
CFHR1
HGNC ID
HGNC:4888
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_002113
RefSeq Synonyms
NM_002113, BC107771, BC016755,
Species
human
UniGene ID
Hs.575869

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.