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human CENPA Over-expression AAV

Name 
AAV-h-CENPA
Cat No 
AAV-204949
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CENPA.

AAV-204949
AAV-h-CENPA

Ready-to-use AAV expressing Human CENPA (centromere protein A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CenH3; CENP-A
Description (Vector)
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
1058
Gene Name (Vector)
centromere protein A
Gene Symbol
CENPA
HGNC ID
HGNC:1851
ORF Size (aa)
423
ORF Size (bp)
423 bp
RefSeq ID
NM_001809
RefSeq Synonyms
NM_001809, NM_001042426, BC002703, BC000881,
Species
human
UniGene ID
Hs.1594

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.