human CDKN1C Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-204879
Availability:
3-5 weeks
Name:
AAV-h-CDKN1C
This is an AAV expressing Human CDKN1C.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CDKN1C
- Gene Name
- cyclin dependent kinase inhibitor 1C
- Gene ID
- 1028
- Gene Synonyms
- BWCR; BWS; KIP2; p57; p57Kip2; WBS
- ORF Size
- 951 bp
- RefSeq#
- BC067842
- Gene Description
- CDKN1C is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
- UniGene ID
- Hs.106070
- HGNC ID
- HGNC:1786
Related Products
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