human CDCA3 Over-expression AAV

Name
AAV-h-CDCA3

Cat No
AAV-204785

Availability
4-5 weeks

This is an AAV expressing Human CDCA3.

AAV-204785

AAV-h-CDCA3

Ready-to-use AAV expressing Human CDCA3 (cell division cycle associated 3). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

cell division cycle-associated protein 3; gene-rich cluster protein C8; GRCC8; TOME-1; trigger of mitotic entry protein 1

Description (eCommerce)

CDCA3/TOME1 is an F-box protein and is part of the SCF complex, an ubiquitin ligase complex that promotes degradation of the mitosis-inhibitory kinase, wee1. CDCA3/TOME1 expression is cell cycle regulated by cis-promoter elements and activated at the G2/M phase. CDCA3/TOME1 levels are also regulated at the protein level via degradation by the APC (anaphase-promoting complex) during G1.

Gene ID

83461

Gene Name (eCommerce)

cell division cycle associated 3

Gene Name (Vector)

cell division cycle associated 3

Gene Symbol

CDCA3

HGNC ID

HGNC:14624

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

807

ORF Size (bp)

807 bp

Protein Name (eCommerce)

Cell division cycle-associated protein 3

RefSeq ID

NM_031299

RefSeq Synonyms

NM_031299, NM_001331019, NM_001297604, NM_001297603, NM_001297602, BC036512, BC002551,

Research Areas

Cell Cycle,Cell Division,Ubiquitination

Research Areas (Faceted)

cell_biology,cell_cycle,genetics

Species

human

Target Sentence

CDCA3/TOME1 is an F-box protein and is part of the SCF complex, an ubiquitin ligase complex that promotes degradation of the mitosis-inhibitory kinase, wee1. CDCA3/TOME1 expression is cell cycle regulated by cis-promoter elements and activated at the G2/M phase. CDCA3/TOME1 levels are also regulated at the protein level via degradation by the APC (anaphase-promoting complex) during G1.

UniGene ID

Hs.524216

UniProt ID (eCommerce)

Q99618

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.