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human CCDC94 Over-expression AAV

Name 
AAV-h-CCDC94
Cat No 
AAV-204398
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CCDC94.

AAV-204398
AAV-h-CCDC94

Ready-to-use AAV expressing Human CCDC94 (coiled-coil domain containing 94). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CCDC94; coiled-coil domain containing 94; coiled-coil domain-containing protein 94; YJU2 splicing factor homolog
Description (eCommerce)
CCDC94 is part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. CCDC94 also plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. CCDC94 may protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BW85].
Gene ID
55702
Gene Name (eCommerce)
YJU2 splicing factor homolog
Gene Name (Vector)
coiled-coil domain containing 94
Gene Symbol
CCDC94
HGNC ID
HGNC:25518
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
972
ORF Size (bp)
972 bp
Protein Name (eCommerce)
Coiled-coil domain-containing protein 94
RefSeq ID
NM_018074
RefSeq Synonyms
NM_018074, BC019096, BC000561,
Research Areas
P53 Signaling,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
CCDC94 is part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. CCDC94 also plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. CCDC94 may protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BW85].
UniGene ID
Hs.21811
UniProt ID (eCommerce)
Q9BW85

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.