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human CBX8 Over-expression AAV

Name 
AAV-h-CBX8
Cat No 
AAV-204204
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CBX8.

AAV-204204
AAV-h-CBX8

Ready-to-use AAV expressing Human CBX8 (chromobox 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
chromobox homolog 8 (Pc class homolog, Drosophila); chromobox protein homolog 8; hPc3; Pc class 3 homolog; PC3; polycomb 3; Polycomb 3 homolog; RC1; rectachrome 1
Description (eCommerce)
CBX8 is part of the polycomb group of proteins that are important in embryogenesis and human tumorigenesis and regulates a number of genes involved in cell growth and survival. There are at least 5 CBX proteins in mammals. CBX proteins associate with the core polycomb repressive complex 1 (PRC1) that functions to maintain the transcriptionally repressive state of genes during development.
Gene ID
57332
Gene Name (eCommerce)
chromobox 8
Gene Name (Vector)
chromobox 8
Gene Symbol
CBX8
HGNC ID
HGNC:15962
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1170
ORF Size (bp)
1170 bp
Protein Name (eCommerce)
Chromobox protein homolog 8
RefSeq ID
NM_020649
RefSeq Synonyms
NM_020649, BC019289, BC009376, BC008937,
Research Areas
Chromatin Remodeling,Complexome,Histone Modification,Polycomb Proteins,RNA Binding,Transcription Factor/Regulator,Ubiquitination
Research Areas (Faceted)
transcription_translation,cell_biology,genetics
Species
human
Target Sentence
CBX8 is part of the polycomb group of proteins that are important in embryogenesis and human tumorigenesis and regulates a number of genes involved in cell growth and survival. There are at least 5 CBX proteins in mammals. CBX proteins associate with the core polycomb repressive complex 1 (PRC1) that functions to maintain the transcriptionally repressive state of genes during development.
UniGene ID
Hs.387258
UniProt ID (eCommerce)
Q9HC52

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.