human C9ORF95 Over-expression AAV

Name
AAV-h-C9ORF95

Cat No
AAV-203857

Availability
4-5 weeks

This is an AAV expressing Human NMRK1.

AAV-203857

AAV-h-C9ORF95

Ready-to-use AAV expressing Human NMRK1 (nicotinamide riboside kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

bA235O14.2; C9orf95; NRK1

Description (Vector)

Nicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide, collectively known as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1, function to synthesize NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor (Bieganowski and Brenner, 2004 (PubMed 15137942)).(supplied by OMIM, Mar 2008)

Gene ID

54981

Gene Name (Vector)

nicotinamide riboside kinase 1

Gene Symbol

NMRK1

HGNC ID

HGNC:26057

ORF Size (aa)

528

RefSeq ID

NM_017881

RefSeq Synonyms

NM_017881, NM_001330679, NM_001330678, NM_001127603, BC036804, BC001366,

Species

human

UniGene ID

Hs.494186

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.