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human C9ORF142 Over-expression AAV

Name 
AAV-h-C9ORF142
Cat No 
AAV-203791
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human C9orf142.

AAV-203791
AAV-h-C9ORF142

Ready-to-use AAV expressing Human C9orf142 (chromosome 9 open reading frame 142). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C9orf142; paralog of XRCC4 and XLF; protein PAXX; XLS; XRCC4-like small protein
Description (eCommerce)
C9orf142 is involved in DNA non-homologous end joining (NHEJ). It may act as a scaffold required to stabilize the Ku heterodimer, composed of XRCC5/Ku80 and XRCC6/Ku70, at DNA ends and thus promote assembly and/or stability of the NHEJ machinery at double-strand break (DSB) sites [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BUH6].
Gene ID
286257
Gene Name (eCommerce)
PAXX, non-homologous end joining factor
Gene Name (Vector)
chromosome 9 open reading frame 142
Gene Symbol
C9orf142
HGNC ID
HGNC:27849
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
615
ORF Size (bp)
615 bp
Protein Name (eCommerce)
Protein PAXX
RefSeq ID
NM_183241
RefSeq Synonyms
NM_183241, NM_001329678, BC002613,
Research Areas
Cell Biology
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
C9orf142 is involved in DNA non-homologous end joining (NHEJ). It may act as a scaffold required to stabilize the Ku heterodimer, composed of XRCC5/Ku80 and XRCC6/Ku70, at DNA ends and thus promote assembly and/or stability of the NHEJ machinery at double-strand break (DSB) sites [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BUH6].
UniGene ID
Hs.409582
UniProt ID (eCommerce)
Q9BUH6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.