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human BTK Over-expression AAV

Name 
AAV-h-BTK
Cat No 
AAV-202333
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BTK.

AAV-202333
AAV-h-BTK

Ready-to-use AAV expressing Human BTK (Bruton tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
Description (Vector)
BTK plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
Gene ID
695
Gene Name (Vector)
Bruton tyrosine kinase
Gene Symbol
BTK
HGNC ID
HGNC:1133
ORF Size (aa)
1980
ORF Size (bp)
1980 bp
RefSeq ID
NM_000061
RefSeq Synonyms
NM_001287345, NM_001287344, NM_000061, BC109080, BC109079,
Species
human
UniGene ID
Hs.159494

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.