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human BIRC3 Over-expression AAV

Name 
AAV-h-BIRC3
Cat No 
AAV-202147
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BIRC3.

AAV-202147
AAV-h-BIRC3

Ready-to-use AAV expressing Human BIRC3 (baculoviral IAP repeat containing 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AIP1; API2; c-IAP2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49
Description (Vector)
BIRC3 encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
Gene ID
330
Gene Name (Vector)
baculoviral IAP repeat containing 3
Gene Symbol
BIRC3
HGNC ID
HGNC:591
ORF Size (aa)
1815
ORF Size (bp)
1815 bp
RefSeq ID
NM_001165
RefSeq Synonyms
NM_182962, NM_001165, BC037420,
Species
human
UniGene ID
Hs.127799

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.