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human BIK Over-expression AAV

Name 
AAV-h-BIK
Cat No 
AAV-202140
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BIK.

AAV-202140
AAV-h-BIK

Ready-to-use AAV expressing Human BIK (BCL2 interacting killer). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BIP1; BP4; NBK
Description (Vector)
BIK shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.
Gene ID
638
Gene Name (Vector)
BCL2 interacting killer
Gene Symbol
BIK
HGNC ID
HGNC:1051
ORF Size (aa)
483
ORF Size (bp)
483 bp
RefSeq ID
NM_001197
RefSeq Synonyms
NM_001197, BC001599,
Species
human
UniGene ID
Hs.475055

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.