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human BICD2 Over-expression AAV

Name 
AAV-h-BICD2
Cat No 
AAV-202136
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BICD2.

AAV-202136
AAV-h-BICD2

Ready-to-use AAV expressing Human BICD2 (BICD cargo adaptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA526D8.1; bicaudal D homolog 2; bic-D 2; coiled-coil protein BICD2; cytoskeleton-like bicaudal D protein homolog 2; homolog of Drosophila bicaudal D; protein bicaudal D homolog 2; SMALED2
Description (eCommerce)
Bicaudal D homolog 2 (BICD2) is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. BICD2 has also been reported to be a phosphorylation target of NIMA related kinase 8 [taken from NCBI Entrez Gene (Gene ID: 23299)].
Description (Vector)
BICD2 is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described.
Gene ID
23299
Gene Name (eCommerce)
BICD cargo adaptor 2
Gene Name (Vector)
BICD cargo adaptor 2
Gene Symbol
BICD2
HGNC ID
HGNC:17208
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2568
ORF Size (bp)
2568 bp
Protein Name (eCommerce)
Protein bicaudal D homolog 2
RefSeq ID
NM_015250
RefSeq Synonyms
NM_015250, NM_001003800, BC073970,
Research Areas
Cytoskeleton,Golgi Apparatus,Neurobiology,Neurodegeneration,Transport
Research Areas (Faceted)
cell_biology,neurobiology
Species
human
Target Sentence
Bicaudal D homolog 2 (BICD2) is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. BICD2 has also been reported to be a phosphorylation target of NIMA related kinase 8 [taken from NCBI Entrez Gene (Gene ID: 23299)].
UniGene ID
Hs.436939
UniProt ID (eCommerce)
Q8TD16

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.