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human BEX2 Over-expression AAV

Name 
AAV-h-BEX2
Cat No 
AAV-202110
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BEX2.

AAV-202110
AAV-h-BEX2

Ready-to-use AAV expressing Human BEX2 (brain expressed X-linked 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BEX1; DJ79P11.1
Description (Vector)
BEX2 belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. BEX2 has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
84707
Gene Name (Vector)
brain expressed X-linked 2
Gene Symbol
BEX2
HGNC ID
HGNC:30933
ORF Size (aa)
387
ORF Size (bp)
387 bp
RefSeq ID
NM_032621
RefSeq Synonyms
NM_032621, NM_001168401, NM_001168400, NM_001168399, BC015522,
Species
human
UniGene ID
Hs.398989

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.