human BEST4 Over-expression AAV

Name 
AAV-h-BEST4
Cat No 
AAV-202101
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BEST4.

AAV-202101
AAV-h-BEST4

Ready-to-use AAV expressing Human BEST4 (bestrophin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
VMD2L2
Description (Vector)
BEST4 is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon.
Gene ID
266675
Gene Name (Vector)
bestrophin 4
Gene Symbol
BEST4
HGNC ID
HGNC:17106
ORF Size (aa)
1422
ORF Size (bp)
1422 bp
RefSeq ID
NM_153274
RefSeq Synonyms
NM_153274, BC101823,
Species
human
UniGene ID
Hs.302513

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.