human BCL2L2 Over-expression AAV
This is an AAV expressing Human BCL2L2.
AAV-202051
AAV-h-BCL2L2
Ready-to-use AAV expressing Human BCL2L2 (BCL2 like 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BCL-W; BCL2-L-2; BCLW; PPP1R51
Description (Vector)
BCL2L2 encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.
Gene ID
599
Gene Name (Vector)
BCL2 like 2
Gene Symbol
BCL2L2
HGNC ID
HGNC:995
ORF Size (aa)
582
ORF Size (bp)
582 bp
RefSeq ID
NM_004050
RefSeq Synonyms
NM_004050, NM_001199839, BC113522, BC104789, BC021198,
Species
human
UniGene ID
Hs.410026
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.