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human BCHE Over-expression AAV

Name 
AAV-h-BCHE
Cat No 
AAV-202025
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BCHE.

AAV-202025
AAV-h-BCHE

Ready-to-use AAV expressing Human BCHE (butyrylcholinesterase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CHE1; CHE2; E1
Description (Vector)
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
Gene ID
590
Gene Name (Vector)
butyrylcholinesterase
Gene Symbol
BCHE
HGNC ID
HGNC:983
ORF Size (aa)
1809
ORF Size (bp)
1809 bp
RefSeq ID
NM_000055
RefSeq Synonyms
NM_000055, BC018141, BC008396,
Species
human
UniGene ID
Hs.420483

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.