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human ATP6V1B2 Over-expression AAV

Name 
AAV-h-ATP6V1B2
Cat No 
AAV-201758
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ATP6V1B2.

AAV-201758
AAV-h-ATP6V1B2

Ready-to-use AAV expressing Human ATP6V1B2 (ATPase H+ transporting V1 subunit B2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ATP6B1B2; ATP6B2; DOOD; HO57; VATB; Vma2; VPP3; ZLS2
Description (Vector)
ATP6V1B2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
Gene ID
526
Gene Name (Vector)
ATPase H+ transporting V1 subunit B2
Gene Symbol
ATP6V1B2
HGNC ID
HGNC:854
ORF Size (aa)
1536
ORF Size (bp)
1536 bp
RefSeq ID
NM_001693
RefSeq Synonyms
NM_001693, BC030640, BC003100,
Species
human
UniGene ID
Hs.295917

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.