human ATP5G2 Over-expression AAV

Name
AAV-h-ATP5G2

Cat No
AAV-201723

Availability
4-5 weeks

This is an AAV expressing Human ATP5G2.

AAV-201723

AAV-h-ATP5G2

Ready-to-use AAV expressing Human ATP5G2 (ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ATP5A

Description (Vector)

ATP5G2 encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins. The protein encoded by this gene is one of three precursors of subunit c. Alternatively spliced transcript variants encoding different isoforms have been identified. ATP5G2 has multiple pseudogenes.

Gene ID

517

Gene Name (Vector)

ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9)

Gene Symbol

ATP5G2

HGNC ID

HGNC:842

ORF Size (aa)

426

ORF Size (bp)

426 bp

RefSeq ID

NM_005176

RefSeq Synonyms

NM_005176, NM_001330269, NM_001002031, BC020826,

Species

human

UniGene ID

Hs.524464

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.