human ATP4B Over-expression AAV

Name
AAV-h-ATP4B

Cat No
AAV-201700

Availability
4-5 weeks

This is an AAV expressing Human ATP4B.

AAV-201700

AAV-h-ATP4B

Ready-to-use AAV expressing Human ATP4B (ATPase H+/K+ transporting beta subunit). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ATP6B

Description (Vector)

ATP4B belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase.

Gene ID

496

Gene Name (Vector)

ATPase H+/K+ transporting beta subunit

Gene Symbol

ATP4B

HGNC ID

HGNC:820

ORF Size (aa)

876

ORF Size (bp)

876 bp

RefSeq ID

NM_000705

RefSeq Synonyms

NM_000705, BC029059,

Species

human

UniGene ID

Hs.434202

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.