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human ATL1 Over-expression AAV

Name 
AAV-h-ATL1
Cat No 
AAV-201652
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ATL1.

AAV-201652
AAV-h-ATL1

Ready-to-use AAV expressing Human ATL1 (atlastin GTPase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AD-FSP; atlastin1; FSP1; GBP3; HSN1D; SPG3; SPG3A
Description (Vector)
ATL1 is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
51062
Gene Name (Vector)
atlastin GTPase 1
Gene Symbol
ATL1
HGNC ID
HGNC:11231
ORF Size (aa)
1677
ORF Size (bp)
1677 bp
RefSeq ID
NM_015915
RefSeq Synonyms
NM_181598, NM_015915, NM_001127713, BC010708,
Species
human
UniGene ID
Hs.584905

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.