human ASB2 Over-expression AAV

Name 
AAV-h-ASB2
Cat No 
AAV-201529
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ASB2.

AAV-201529
AAV-h-ASB2

Ready-to-use AAV expressing Human ASB2 (ankyrin repeat and SOCS box containing 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ASB-2
Description (Vector)
ASB2 encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. ASB2 plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
51676
Gene Name (Vector)
ankyrin repeat and SOCS box containing 2
Gene Symbol
ASB2
HGNC ID
HGNC:16012
ORF Size (aa)
1764
ORF Size (bp)
1764 bp
RefSeq ID
NM_016150
RefSeq Synonyms
NM_016150, NM_001202429, BC032354,
Species
human
UniGene ID
Hs.510327

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.