human ARHGEF15 Over-expression AAV

Name
AAV-h-ARHGEF15

Cat No
AAV-201358

Availability
4-5 weeks

This is an AAV expressing Human ARHGEF15.

AAV-201358

AAV-h-ARHGEF15

Ready-to-use AAV expressing Human ARHGEF15 (Rho guanine nucleotide exchange factor 15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ARGEF15; E5; Ephexin5; Vsm-RhoGEF

Description (Vector)

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene.

Gene ID

22899

Gene Name (Vector)

Rho guanine nucleotide exchange factor 15

Gene Symbol

ARHGEF15

HGNC ID

HGNC:15590

ORF Size (aa)

2526

ORF Size (bp)

2526 bp

RefSeq ID

NM_173728

RefSeq Synonyms

NM_173728, NM_025014, BC036749,

Species

human

UniGene ID

Hs.443109

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.