human APOBEC1 Over-expression AAV

Name
AAV-h-APOBEC1

Cat No
AAV-201176

Availability
4-5 weeks

This is an AAV expressing Human APOBEC1.

AAV-201176

AAV-h-APOBEC1

Ready-to-use AAV expressing Human APOBEC1 (apolipoprotein B mRNA editing enzyme catalytic subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

APOBEC-1; BEDP; CDAR1; HEPR

Description (Vector)

APOBEC1 encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs.

Gene ID

339

Gene Name (Vector)

apolipoprotein B mRNA editing enzyme catalytic subunit 1

Gene Symbol

APOBEC1

HGNC ID

HGNC:604

ORF Size (aa)

711

ORF Size (bp)

711 bp

RefSeq ID

NM_001644

RefSeq Synonyms

NM_005889, NM_001644, NM_001304566, BC172305,

Species

human

UniGene ID

Hs.560

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.