human APCS Over-expression AAV

Name 
AAV-h-APCS
Cat No 
AAV-201132
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human APCS.

AAV-201132
AAV-h-APCS

Ready-to-use AAV expressing Human APCS (amyloid P component, serum). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HEL-S-92n; PTX2; SAP
Description (Vector)
APCS is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Gene ID
325
Gene Name (Vector)
amyloid P component, serum
Gene Symbol
APCS
HGNC ID
HGNC:584
ORF Size (aa)
672
ORF Size (bp)
672 bp
RefSeq ID
NM_001639
RefSeq Synonyms
NM_001639, BC007058, BC007039,
Species
human
UniGene ID
Hs.507080

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.