human AP4E1 Over-expression AAV

Name 
AAV-h-AP4E1
Cat No 
AAV-201109
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human AP4E1.

AAV-201109
AAV-h-AP4E1

Ready-to-use AAV expressing Human AP4E1 (adaptor related protein complex 4 epsilon 1 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CPSQ4; SPG51; STUT1
Description (Vector)
AP4E1 encodes a member of the adaptor complexes large subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is a large subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Disruption of this gene may be associated with cerebral palsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
23431
Gene Name (Vector)
adaptor related protein complex 4 epsilon 1 subunit
Gene Symbol
AP4E1
HGNC ID
HGNC:573
ORF Size (aa)
3414
ORF Size (bp)
3414 bp
RefSeq ID
NM_007347
RefSeq Synonyms
NM_007347, NM_001252127, BC130466, BC126308,
Species
human
UniGene ID
Hs.413366

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.