human AP1GBP1 Over-expression AAV

Name 
AAV-h-AP1GBP1
Cat No 
AAV-201079
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SYNRG.

AAV-201079
AAV-h-AP1GBP1

Ready-to-use AAV expressing Human SYNRG (synergin gamma). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
adaptor-related protein complex 1 gamma subunit-binding protein 1; AP1 gamma subunit binding protein 1; AP1 subunit gamma-binding protein 1; AP1GBP1; gamma-synergin; synergin gamma; SYNG
Description (eCommerce)
Gamma-synergin interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. Gamma-synergin may act to connect the AP1 complex to other proteins [taken from NCBI Entrez Gene (Gene ID: 11276)].
Description (Vector)
SYNRG encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Gene ID
11276
Gene Name (eCommerce)
synergin gamma
Gene Name (Vector)
synergin gamma
Gene Symbol
SYNRG
HGNC ID
HGNC:557
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3675
ORF Size (bp)
3675 bp
Protein Name (eCommerce)
Synergin gamma
RefSeq ID
NM_007247
RefSeq Synonyms
NM_198882, NM_080550, NM_007247, NM_001163547, NM_001163546, NM_001163545, NM_001163544, BC143478, BC143476, BC117313, BC090930,
Research Areas
Golgi Apparatus,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Gamma-synergin interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. Gamma-synergin may act to connect the AP1 complex to other proteins [taken from NCBI Entrez Gene (Gene ID: 11276)].
UniGene ID
Hs.655178
UniProt ID (eCommerce)
Q9UMZ2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.