human ANXA5 Over-expression AAV

Name 
AAV-h-ANXA5
Cat No 
AAV-201057
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ANXA5.

AAV-201057
AAV-h-ANXA5

Ready-to-use AAV expressing Human ANXA5 (annexin A5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
anchorin CII; annexin A5; annexin V; annexin-5; ANX5; calphobindin I; CBP-I; endonexin II; ENX2; epididymis secretory protein Li 7; HEL-S-7; lipocortin V; PAP-I; placental anticoagulant protein 4; placental anticoagulant protein I; PP4; RPRGL3; thromboplastin inhibitor; VAC-alpha; vascular anticoagulant-alpha
Description (eCommerce)
Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08758].
Description (Vector)
ANXA5 belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
Gene ID
308
Gene Name (eCommerce)
annexin A5
Gene Name (Vector)
annexin A5
Gene Symbol
ANXA5
HGNC ID
HGNC:543
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
963
ORF Size (bp)
963 bp
Protein Name (eCommerce)
Annexin A5
RefSeq ID
NM_001154
RefSeq Synonyms
NM_001154, BC018671, BC012822, BC012804, BC004993, BC001429,
Research Areas
Apoptosis,Cardiovascular,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,cardiovascular
Species
human
Target Sentence
Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08758].
UniGene ID
Hs.705884
UniProt ID (eCommerce)
P08758

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.