human ANO6 Over-expression AAV

Name
AAV-h-ANO6

Cat No
AAV-201021

Availability
4-5 weeks

Categories
AAV, Over-Expression

This is an AAV expressing Human ANO6.

AAV-201021

AAV-h-ANO6

Ready-to-use AAV expressing Human ANO6 (anoctamin 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BDPLT7; SCTS; TMEM16F

Description (Vector)

ANO6 encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

196527

Gene Name (Vector)

anoctamin 6

Gene Symbol

ANO6

HGNC ID

HGNC:25240

ORF Size (aa)

2796

ORF Size (bp)

2796 bp

RefSeq ID

NM_001025356

RefSeq Synonyms

NM_001204803, NM_001142680, NM_001142679, NM_001142678, NM_001025356, BC136445, BC098410,

Species

human

UniGene ID

Hs.696326

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.