human ANKRD28 Over-expression AAV

Name 
AAV-h-ANKRD28
Cat No 
AAV-200964
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ANKRD28.

AAV-200964
AAV-h-ANKRD28

Ready-to-use AAV expressing Human ANKRD28 (ankyrin repeat domain 28). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ankyrin repeat domain-containing protein 28; phosphatase interactor targeting K protein; phosphatase interactor targeting protein hnRNP K; PITK; PP6-ARS-A; PPP1R65; protein phosphatase 1, regulatory subunit 65; protein phosphatase 6 ankyrin repeat subunit A; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A; serine/threonine-protein phosphatase 6 regulatory subunit ARS-A
Description (eCommerce)
ANKRD28/PITK is a regulatory subunit of protein phosphatase-1 (PP1) that targets the PP1 catalytic subunit to nuclear foci to dephosphorylate and modulate the transcriptional activity of heterogeneous nuclear ribonucleoprotein K (hnRNPK). ANKRD28/PITK has been shown to be phosphorylated and regulated by calcium/calmodulin-dependent kinase II-delta (CaMKIIdelta) and glycogen synthase kinase-3 (GSK3).
Gene ID
23243
Gene Name (eCommerce)
ankyrin repeat domain 28
Gene Name (Vector)
ankyrin repeat domain 28
Gene Symbol
ANKRD28
HGNC ID
HGNC:29024
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3162
ORF Size (bp)
3162 bp
Protein Name (eCommerce)
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
RefSeq ID
NM_015199
RefSeq Synonyms
NM_015199, NM_001195099, NM_001195098, BC166612,
Research Areas
Kinase/Phosphatase,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
ANKRD28/PITK is a regulatory subunit of protein phosphatase-1 (PP1) that targets the PP1 catalytic subunit to nuclear foci to dephosphorylate and modulate the transcriptional activity of heterogeneous nuclear ribonucleoprotein K (hnRNPK). ANKRD28/PITK has been shown to be phosphorylated and regulated by calcium/calmodulin-dependent kinase II-delta (CaMKIIdelta) and glycogen synthase kinase-3 (GSK3).
UniGene ID
Hs.335239
UniProt ID (eCommerce)
O15084

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.