human AMFR Over-expression AAV

Name 
AAV-h-AMFR
Cat No 
AAV-200844
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human AMFR.

AAV-200844
AAV-h-AMFR

Ready-to-use AAV expressing Human AMFR (autocrine motility factor receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AMF receptor; Autocrine motility factor receptor; E3 ubiquitin-protein ligase AMFR; GP78; RING finger protein 45; RING-type E3 ubiquitin transferase AMFR; RNF45
Description (eCommerce)
gp78 is the specific receptor for autocrine motility factor. gp78 is also known as autocrine motility factor receptor, isoform 1(AMFR). Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells.
Description (Vector)
This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins.
Gene ID
267
Gene Name (eCommerce)
autocrine motility factor receptor
Gene Name (Vector)
autocrine motility factor receptor
Gene Symbol
AMFR
HGNC ID
HGNC:463
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1932
ORF Size (bp)
1932 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase AMFR
RefSeq ID
NM_001144
RefSeq Synonyms
NM_001323512, NM_001323511, NM_001144, BC069197,
Research Areas
Aging,Neurobiology,Signal Transduction,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology,neurobiology,signal_transduction
Species
human
Target Sentence
gp78 is the specific receptor for autocrine motility factor. gp78 is also known as autocrine motility factor receptor, isoform 1(AMFR). Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells.
UniGene ID
Hs.295137
UniProt ID (eCommerce)
Q9UKV5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.