human ALG8 Over-expression AAV

Name
AAV-h-ALG8

Cat No
AAV-200781

Availability
4-5 weeks

This is an AAV expressing Human ALG8.

AAV-200781

AAV-h-ALG8

Ready-to-use AAV expressing Human ALG8 (ALG8, alpha-1,3-glucosyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CDG1H

Description (Vector)

ALG8 encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins. Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene ID

79053

Gene Name (Vector)

ALG8, alpha-1,3-glucosyltransferase

Gene Symbol

ALG8

HGNC ID

HGNC:23161

ORF Size (aa)

1581

ORF Size (bp)

1581 bp

RefSeq ID

NM_024079

RefSeq Synonyms

NM_024079, NM_001007027, BC001133,

Species

human

UniGene ID

Hs.503368

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.