human AKR7A2 Over-expression AAV

Name 
AAV-h-AKR7A2
Cat No 
AAV-200694
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human AKR7A2.

AAV-200694
AAV-h-AKR7A2

Ready-to-use AAV expressing Human AKR7A2 (aldo-keto reductase family 7 member A2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AFAR; AFAR1; AFB1-AR1; AKR7
Description (Vector)
AKR7A2 belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde.
Gene ID
8574
Gene Name (Vector)
aldo-keto reductase family 7 member A2
Gene Symbol
AKR7A2
HGNC ID
HGNC:389
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_003689
RefSeq Synonyms
NM_003689, NM_001320979, BC013996, BC012171, BC011586, BC010852, BC004111,
Species
human
UniGene ID
Hs.571886

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.