human AKR1C4 Over-expression AAV

Name 
AAV-h-AKR1C4
Cat No 
AAV-200688
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human AKR1C4.

AAV-200688
AAV-h-AKR1C4

Ready-to-use AAV expressing Human AKR1C4 (aldo-keto reductase family 1 member C4). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3-alpha-HSD; C11; CDR; CHDR; DD-4; DD4; HAKRA
Description (Vector)
AKR1C4 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Gene ID
1109
Gene Name (Vector)
aldo-keto reductase family 1 member C4
Gene Symbol
AKR1C4
HGNC ID
HGNC:387
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_001818
RefSeq Synonyms
NM_001818, BC020744,
Species
human
UniGene ID
Hs.567245

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.