human AICDA Over-expression AAV

Name 
AAV-h-AICDA
Cat No 
AAV-200616
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human AICDA.

AAV-200616
AAV-h-AICDA

Ready-to-use AAV expressing Human AICDA (activation induced cytidine deaminase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AID; ARP2; CDA2; HEL-S-284; HIGM2
Description (Vector)
AICDA encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
Gene ID
57379
Gene Name (Vector)
activation induced cytidine deaminase
Gene Symbol
AICDA
HGNC ID
HGNC:13203
ORF Size (aa)
597
ORF Size (bp)
597 bp
RefSeq ID
NM_020661
RefSeq Synonyms
NM_020661, NM_001330343, BC006296,
Species
human
UniGene ID
Hs.149342

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.