human AGPAT2 Over-expression AAV

Name
AAV-h-AGPAT2

Cat No
AAV-200569

Availability
4-5 weeks

This is an AAV expressing Human AGPAT2.

AAV-200569

AAV-h-AGPAT2

Ready-to-use AAV expressing Human AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1-AGPAT2; BSCL; BSCL1; LPAAB; LPAAT-beta

Description (Vector)

AGPAT2 encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene ID

10555

Gene Name (Vector)

1-acylglycerol-3-phosphate O-acyltransferase 2

Gene Symbol

AGPAT2

HGNC ID

HGNC:325

ORF Size (aa)

837

ORF Size (bp)

837 bp

RefSeq ID

NM_006412

RefSeq Synonyms

NM_006412, NM_001012727, BC019292, BC004529, BC000026,

Species

human

UniGene ID

Hs.320151

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.