human ADRBK2 Over-expression AAV

Name
AAV-h-ADRBK2

Cat No
AAV-200512

Availability
4-5 weeks

This is an AAV expressing Human GRK3.

AAV-200512

AAV-h-ADRBK2

Ready-to-use AAV expressing Human GRK3 (G protein-coupled receptor kinase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ADRBK2; BARK2

Description (Vector)

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

Gene ID

157

Gene Name (Vector)

G protein-coupled receptor kinase 3

Gene Symbol

GRK3

HGNC ID

HGNC:290

ORF Size (aa)

1164

RefSeq ID

NM_005160

RefSeq Synonyms

NM_005160, BC036797,

Species

human

UniGene ID

Hs.657494

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.