human ADRB2 Over-expression AAV

Name 
AAV-h-ADRB2
Cat No 
AAV-200506
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ADRB2.

AAV-200506
AAV-h-ADRB2

Ready-to-use AAV expressing Human ADRB2 (adrenoceptor beta 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADRB2R; ADRBR; B2AR; BAR; BETA2AR
Description (Vector)
ADRB2 encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. ADRB2 is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Gene ID
154
Gene Name (Vector)
adrenoceptor beta 2
Gene Symbol
ADRB2
HGNC ID
HGNC:286
ORF Size (aa)
1242
ORF Size (bp)
1242 bp
RefSeq ID
NM_000024
RefSeq Synonyms
NM_000024, BC073856, BC063486, BC012481,
Species
human
UniGene ID
Hs.591251

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.