human ADRA1B Over-expression AAV

Name 
AAV-h-ADRA1B
Cat No 
AAV-200499
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ADRA1B.

AAV-200499
AAV-h-ADRA1B

Ready-to-use AAV expressing Human ADRA1B (adrenoceptor alpha 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADRA1; ALPHA1BAR
Description (Vector)
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Gene ID
147
Gene Name (Vector)
adrenoceptor alpha 1B
Gene Symbol
ADRA1B
HGNC ID
HGNC:278
ORF Size (aa)
1563
ORF Size (bp)
1563 bp
RefSeq ID
NM_000679
RefSeq Synonyms
NM_000679, BC136569, BC136568,
Species
human
UniGene ID
Hs.368632

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.