human ADH5 Over-expression AAV

Name 
AAV-h-ADH5
Cat No 
AAV-200460
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ADH5.

AAV-200460
AAV-h-ADH5

Ready-to-use AAV expressing Human ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADH-3; ADHX; FALDH; FDH; GSH-FDH; GSNOR; HEL-S-60p
Description (Vector)
ADH5 encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
Gene ID
128
Gene Name (Vector)
alcohol dehydrogenase 5 (class III), chi polypeptide
Gene Symbol
ADH5
HGNC ID
HGNC:253
ORF Size (aa)
1125
ORF Size (bp)
1125 bp
RefSeq ID
NM_000671
RefSeq Synonyms
NM_000671, BC070491, BC014665,
Species
human
UniGene ID
Hs.78989

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.