human ADARB1 Over-expression AAV

Name
AAV-h-ADARB1

Cat No
AAV-200407

Availability
4-5 weeks

This is an AAV expressing Human ADARB1.

AAV-200407

AAV-h-ADARB1

Ready-to-use AAV expressing Human ADARB1 (adenosine deaminase, RNA specific B1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ADAR2; DRABA2; DRADA2; RED1

Description (Vector)

ADARB1 encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.

Gene ID

104

Gene Name (Vector)

adenosine deaminase, RNA specific B1

Gene Symbol

ADARB1

HGNC ID

HGNC:226

ORF Size (aa)

2106

ORF Size (bp)

2106 bp

RefSeq ID

NM_001112

RefSeq Synonyms

NM_015834, NM_015833, NM_001346688, NM_001346687, NM_001160230, NM_001112, BC065545,

Species

human

UniGene ID

Hs.474018

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.