human ADAMTSL2 Over-expression AAV

Name 
AAV-h-ADAMTSL2
Cat No 
AAV-200397
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ADAMTSL2.

AAV-200397
AAV-h-ADAMTSL2

Ready-to-use AAV expressing Human ADAMTSL2 (ADAMTS like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GPHYSD1
Description (Vector)
ADAMTSL2 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.
Gene ID
9719
Gene Name (Vector)
ADAMTS like 2
Gene Symbol
ADAMTSL2
HGNC ID
HGNC:14631
ORF Size (aa)
2856
ORF Size (bp)
2856 bp
RefSeq ID
NM_014694
RefSeq Synonyms
NM_014694, NM_001145320, BC050544,
Species
human
UniGene ID
Hs.522543

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.