human ADAMTS5 Over-expression AAV

Name 
AAV-h-ADAMTS5
Cat No 
AAV-200390
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ADAMTS5.

AAV-200390
AAV-h-ADAMTS5

Ready-to-use AAV expressing Human ADAMTS5 (ADAM metallopeptidase with thrombospondin type 1 motif 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADAM-TS 11; ADAM-TS 5; ADAM-TS5; ADAMTS-11; ADAMTS-5; ADAMTS11; ADMP-2
Description (Vector)
ADAMTS5 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.
Gene ID
11096
Gene Name (Vector)
ADAM metallopeptidase with thrombospondin type 1 motif 5
Gene Symbol
ADAMTS5
HGNC ID
HGNC:221
ORF Size (aa)
2793
ORF Size (bp)
2793 bp
RefSeq ID
NM_007038
RefSeq Synonyms
NM_007038, BC093777, BC093775,
Species
human
UniGene ID
Hs.58324

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.