human ADAM9 Over-expression AAV

Name 
AAV-h-ADAM9
Cat No 
AAV-200372
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ADAM9.

AAV-200372
AAV-h-ADAM9

Ready-to-use AAV expressing Human ADAM9 (ADAM metallopeptidase domain 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADAM 9; ADAM metallopeptidase domain 9 (meltrin gamma); cellular disintegrin-related protein; cone rod dystrophy 9; CORD9; disintegrin and metalloproteinase domain-containing protein 9; MCMP; MDC9; Meltrin-gamma; metalloprotease/disintegrin/cysteine-rich protein 9; Mltng; myeloma cell metalloproteinase
Description (eCommerce)
ADAM9 a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM9 interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor [taken from NCBI Entrez Gene (Gene ID: 8754)].
Description (Vector)
ADAM9 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene.
Gene ID
8754
Gene Name (eCommerce)
ADAM metallopeptidase domain 9
Gene Name (Vector)
ADAM metallopeptidase domain 9
Gene Symbol
ADAM9
HGNC ID
HGNC:216
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1968
ORF Size (bp)
1968 bp
Protein Name (eCommerce)
Disintegrin and metalloproteinase domain-containing protein 9
RefSeq ID
NM_003816
RefSeq Synonyms
NM_003816, BC143923, BC126406,
Research Areas
Cancer,EGFR Signaling,Immunology,Metabolism/Metabolic Process,Signal Transduction,T-cell Receptor Signaling,TGF-beta Signaling
Research Areas (Faceted)
cancer,cell_biology,immunology,metabolism,signal_transduction
Species
human
Target Sentence
ADAM9 a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM9 interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor [taken from NCBI Entrez Gene (Gene ID: 8754)].
UniGene ID
Hs.591852
UniProt ID (eCommerce)
Q13443

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.