human ACVR1B Over-expression AAV

Name
AAV-h-ACVR1B

Cat No
AAV-200323

Availability
4-5 weeks

This is an AAV expressing Human ACVR1B.

AAV-200323

AAV-h-ACVR1B

Ready-to-use AAV expressing Human ACVR1B (activin A receptor type 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ACTRIB; ACVRLK4; ALK4; SKR2

Description (Vector)

ACVR1B encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.

Gene ID

Gene Name (Vector)

activin A receptor type 1B

Gene Symbol

ACVR1B

HGNC ID

HGNC:172

ORF Size (aa)

1518

ORF Size (bp)

1518 bp

RefSeq ID

NM_004302

RefSeq Synonyms

NM_020328, NM_020327, NM_004302, BC040531, BC000254,

Species

human

UniGene ID

Hs.438918

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.