human ACTN3 Over-expression AAV

Name
AAV-h-ACTN3

Cat No
AAV-200303

Availability
4-5 weeks

This is an AAV expressing Human ACTN3.

AAV-200303

AAV-h-ACTN3

Ready-to-use AAV expressing Human ACTN3 (actinin alpha 3 (gene/pseudogene)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

ACTN3 encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants. The reference genome contains the non-coding allele. The non-functional allele of this gene is associated with elite athlete status.

Gene ID

Gene Name (Vector)

actinin alpha 3 (gene/pseudogene)

Gene Symbol

ACTN3

HGNC ID

HGNC:165

ORF Size (aa)

2706

ORF Size (bp)

2706 bp

RefSeq ID

NM_001104

RefSeq Synonyms

NM_001258371, NM_001104, BC099649, BC099647,

Species

human

UniGene ID

Hs.654432

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.