human ACTN2 Over-expression AAV

Name 
AAV-h-ACTN2
Cat No 
AAV-200301
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ACTN2.

AAV-200301
AAV-h-ACTN2

Ready-to-use AAV expressing Human ACTN2 (actinin alpha 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CMD1AA; CMH23
Description (Vector)
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles.
Gene ID
88
Gene Name (Vector)
actinin alpha 2
Gene Symbol
ACTN2
HGNC ID
HGNC:164
ORF Size (aa)
2685
ORF Size (bp)
2685 bp
RefSeq ID
NM_001103
RefSeq Synonyms
NM_001278344, NM_001278343, NM_001103, BC051770, BC047901,
Species
human
UniGene ID
Hs.498178

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.