human ACP2 Over-expression AAV

Name
AAV-h-ACP2

Cat No
AAV-200225

Availability
4-5 weeks

This is an AAV expressing Human ACP2.

AAV-200225

AAV-h-ACP2

Ready-to-use AAV expressing Human ACP2 (acid phosphatase 2, lysosomal). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

LAP

Description (Vector)

ACP2 encodes the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The encoded protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Mutations in this gene or in the related alpha subunit gene cause acid phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene ID

Gene Name (Vector)

acid phosphatase 2, lysosomal

Gene Symbol

ACP2

HGNC ID

HGNC:123

ORF Size (aa)

1272

ORF Size (bp)

1272 bp

RefSeq ID

NM_001610

RefSeq Synonyms

NM_001610, NM_001302492, NM_001302491, NM_001302490, NM_001302489, NM_001131064, BC093010, BC003160,

Species

human

UniGene ID

Hs.532492

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.