human ACOX3 Over-expression AAV

Name
AAV-h-ACOX3

Cat No
AAV-200222

Availability
4-5 weeks

This is an AAV expressing Human ACOX3.

AAV-200222

AAV-h-ACOX3

Ready-to-use AAV expressing Human ACOX3 (acyl-CoA oxidase 3, pristanoyl). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined.

Gene ID

8310

Gene Name (Vector)

acyl-CoA oxidase 3, pristanoyl

Gene Symbol

ACOX3

HGNC ID

HGNC:121

ORF Size (aa)

1875

ORF Size (bp)

1875 bp

RefSeq ID

NM_003501

RefSeq Synonyms

NM_003501, NM_001101667, BC017053,

Species

human

UniGene ID

Hs.479122

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.