human ASIC3 Over-expression AAV

Name 
AAV-h-ASIC3
Cat No 
AAV-200175
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ASIC3.

AAV-200175
AAV-h-ASIC3

Ready-to-use AAV expressing Human ASIC3 (acid sensing ion channel subunit 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACCN3; DRASIC; SLNAC1; TNaC1
Description (Vector)
ASIC3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.
Gene ID
9311
Gene Name (Vector)
acid sensing ion channel subunit 3
Gene Symbol
ASIC3
HGNC ID
HGNC:101
ORF Size (aa)
1650
ORF Size (bp)
1650 bp
RefSeq ID
NM_004769
RefSeq Synonyms
NM_020322, NM_020321, NM_004769, BC156796,
Species
human
UniGene ID
Hs.647113

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.