human ACAD8 Over-expression AAV

Name
AAV-h-ACAD8

Cat No
AAV-200151

Availability
4-5 weeks

This is an AAV expressing Human ACAD8.

AAV-200151

AAV-h-ACAD8

Ready-to-use AAV expressing Human ACAD8 (acyl-CoA dehydrogenase family member 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ACAD-8; ARC42

Description (Vector)

ACAD8 encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.

Gene ID

27034

Gene Name (Vector)

acyl-CoA dehydrogenase family member 8

Gene Symbol

ACAD8

HGNC ID

HGNC:87

ORF Size (aa)

1248

ORF Size (bp)

1248 bp

RefSeq ID

NM_014384

RefSeq Synonyms

NM_014384, BC001964,

Species

human

UniGene ID

Hs.14791

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.